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List of papers
CURRICULUM VITAE |
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Anders Hallberg, Department of Medicinal Chemistry, BMC, Uppsala University Box 574, S-751 23 Uppsala |
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BORN: April 29, 1945 NATIONALITY: Swedish |
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Professional preparation |
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Master of Science (Chemistry/Physics) |
University of Lund |
1969 |
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Specialist teacher (B. Ed. ämneslärar utb) |
Malmö |
1970 |
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PhD (Chemistry) |
University of Lund |
1980 |
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Assistant professor (docent) |
University of Lund |
1983 |
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Doctorial Dissertation: Jan. 1980 in Organic Chemistry. Title: Methoxythiophenes and Related Systems. |
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Supervisor: Prof. Salo Gronowitz |
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Appointments |
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President |
Uppsala University |
2006- |
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Dean Faculty of Pharmacy |
Uppsala University |
2005-06 |
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Deputy vice President (Medicine/Pharmacy) |
Uppsala University |
2002-05 |
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Dean for Research, Faculty of Pharmacy |
Uppsala University |
1996-02 |
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Head of the Dep. of Org. Pharm. Chem. |
Uppsala University |
1991-06 |
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Professor in Medicinal Chemistry |
Uppsala University |
1990- |
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Director, Head of Medicinal Chemistry |
Astra, Lund |
1988-90 |
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Associate Director |
Astra, Lund |
1986-88 |
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Associate professor (forskare, NFR grant) |
The Chemical Center, Lund |
1983-86 |
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Assistant professor |
University of Arizona, Tucson |
1981-82 |
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Research associate (6 months) |
University of Arizona, Tucson |
1980 |
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Research scientist (6 months) |
Nobel Kemi, Karlskoga |
1980 |
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Assistant research fellow |
The Chemical Center, Lund |
1973-79 |
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Specialist teacher |
Schools in Sweden |
1970-73 |
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Miscellaneous |
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Chairman of the Medicinal Chemistry Section, Swedish Academy of Pharmaceutical Sciences |
1992-97 |
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Vice Chairman of the Board of the Faculties of Medicine and Pharmacy |
2002-05 |
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Member of the Board of Carolina Rediviva |
2002-05 |
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Member of the Board of Laboratory Animal Resources at Uppsala University |
2004-05 |
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Member of the Board of Uppsala University Holding Company |
2005-06 |
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Chairman of the Steering Committee of MedFarm DoIT |
2003-05 |
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Member of the Chemistry Evaluation Committee, NFR |
1997-00 |
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Member of the Chemistry Steering Committee, NFR |
1998-00 |
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Chairman Evaluation Panel F (Chemistry), Swedish Research Council (VR) |
2001-05 |
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Member of Uppsala University Foundations Management of Estates and Funds |
2006- |
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Member of the County Administrative Board |
2007- |
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Member of the Royal Society of Sciences in Uppsala |
1994- |
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Member of the Royal Academy of Art and Sciences in Uppsala |
2004- |
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Member of the Royal Physiographic Society in Lund |
2005- |
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Member of the Royal Academy of Sciences |
2006- |
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Member of the Royal Academy of Engineering Sciences |
2007- |
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Section Editor, European Journal of Pharmaceutical Sciences |
1998-05 |
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Fabian Gyllenbergs Award from the Royal Physiographic Society in Lund, |
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for best PhD thesis (from a three year period) in Lund in chemistry |
1981 |
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Senior Individual Grant Award to outstanding senior scientist (SSF) |
1998 |
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Ulla and Stig Holmquist´s National Prize in Organic Chemistry |
2004 |
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The Oscar Carlsson medal from the Swedish Chemical Society for excellence |
2005 |
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Pedagogiska priset 2006 from The Pharmacy Student Union |
2006 |
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Honored with H. M. the King's Medal for distinguished achievements in education and research |
2008 |
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Scientific Adviser AstraZeneca Lund |
1990-99 |
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Scientific Adviser AstraZeneca Mölndal |
2000-06 |
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Numerous patents; over 240 publications in international journals; inventor of two Candidate Drugs evaluated in clinic. |
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PhD student supervision |
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PhD students: Kostas Karabelas, 1988; Carl-Magnus Andersson, 1988; Kristina Nilsson,1990; Mats Larhed, 1997; Lena Ripa, 1997; Johan Hultén, 1999; Susanna Lindman, 2001; Kristofer Olofsson, 2001; Mathias Alterman, 2001; Malin Graffner-Nordberg, 2001; Petra Johannesson, 2002; Daniel Nöteberg, 2003; Anja Johansson, 2003; Karl S. A. Vallin, 2003; Peter Nilsson, 2003; Ulrika Rosenström, 2004; Karolina Ersmark, 2005; Johan Wannberg, 2005; Anna Ax, 2005; Anna Arefalk, 2005; Jennie Georgsson 2006; Jenny Ekegren 2006; Per-Anders Enquist 2006; Robert Rönn 2007; Charlotta Wallinder 2008. |
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Research interests |
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The research interests encompass a range of protein targets of pharmaceutical relevance, including
proteases and G-protein coupled receptors (GPCRs). One of the primary themes is to identify novel
and selective low molecular weight ligands for these targets. New strategies are developed for both the
design and for the synthesis of small, drug-like molecules. Lead compounds are optimized using
computer-aided techniques and are preferentially synthesized using high-speed chemistry and new
efficient transition metal-catalyzed reactions developed in our laboratory. Considerable efforts have in
particular been devoted to the development of new robust and useful palladium-catalyzed C-C bond
forming reactions. Major indications that are addressed are infections caused by HIV and HCV
(Hepatitis C Virus) as well as the infectious disease Malaria. In addition, basic research is conducted
to identify novel ligands that interfere with proteins in the renin/angiotensin system. The first drug-like
selective and potent angiotensin II, type II receptor agonist with a high oral bioavailability was
recently discovered. |
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