N. F. K. Kaiser, U. Bremberg, M. Larhed, C. Moberg, and A. Hallberg:
Microwave-mediated palladium-catalyzed asymmetric allylic alkylation; an example of highly selective fast chemistry.
Journal of Organometallic Chemistry, 603, 2-5 (2000).
M. Alterman and A. Hallberg:
Fast microwave-assisted preparation of aryl and vinyl nitriles and the corresponding tetrazoles from organo-halides.
Journal of Organic Chemistry, 65, 7984-7989 (2000).
J. Rostin, A. L. Smeds, and E. Akerblom:
B-domain deleted recombinant coagulation factor VIII modified with monomethoxy polyethylene glycol.
Bioconjugate Chemistry, 11, 387-396 (2000).
S. Lindman, G. Lindeberg, F. Nyberg, A. Karlen, and A. Hallberg:
Comparison of three gamma-turn mimetic scaffolds incorporated into angiotensin II.
Bioorganic & Medicinal Chemistry, 8, 2375-2383 (2000).
S. Lindstrom, L. Ripa, and A. Hallberg:
Synthesis of two conformationally constrained analogues of the minor tobacco alkaloid anabasine.
Organic Letters, 2, 2291-2293 (2000).
K. Oscarsson, B. Classon, I. Kvarnstrom, A. Hallberg, and B. Samuelsson:
Solid phase assisted synthesis of HIV-1 protease inhibitors. Expedient entry to unsymmetrical substitution of a C-2 symmetric template.
Canadian Journal of Chemistry-Revue Canadienne De Chimie, 78, 829-837 (2000).
O. Belda, N. F. Kaiser, U. Bremberg, M. Larhed, A. Hallberg, and C. Moberg:
Highly stereo- and regioselective allylations catalyzed by Mo- pyridylamide complexes: Electronic and steric effects of the ligand.
Journal of Organic Chemistry, 65, 5868-5870 (2000).
K. Olofsson, M. Larhed, and A. Hallberg:
Highly regioselective palladium-catalyzed beta-arylation of N,N-dialkylallylamines.
Journal of Organic Chemistry, 65, 7235-7239 (2000).
A. Johansson, E. Akerblom, K. Ersmark, G. Lindeberg, and A. Hallberg:
An improved procedure for N- to C-directed (inverse) solid- phase peptide synthesis.
Journal of Combinatorial Chemistry, 2, 496-507 (2000).
M. Graffner-Nordberg, J. Marelius, S. Ohlsson, A. Persson, G. Swedberg, P. Andersson, S. E. Andersson, J. Aqvist, and A. Hallberg:
Computational predictions of binding affinities to dihydrofolate reductase: Synthesis and biological evaluation of methotrexate analogues.
Journal of Medicinal Chemistry, 43, 3852-3861 (2000).
K. S. A. Vallin, M. Larhed, K. Johansson, and A. Hallberg:
Highly selective palladium-catalyzed synthesis of protected alpha,beta-unsaturated methyl ketones and 2-alkoxy-1,3- butadienes. High-speed chemistry by microwave flash heating.
Journal of Organic Chemistry, 65, 4537-4542 (2000).
N. F. K. Kaiser, U. Bremberg, M. Larhed, C. Moberg, and A. Hallberg:
Fast, convenient, and efficient molybdenum-catalyzed asymmetric allylic alkylation under noninert conditions: An example of microwave-promoted fast chemistry.
Angewandte Chemie-International Edition, 39, 3596-3598 (2000).
J. Wachtmeister, A. Muhlman, B. Classon, I. Kvarnstrom, A. Hallberg, and B. Samuelsson:
Impact of the central hydroxyl groups on the activity of symmetrical HIV-1 protease inhibitors derived from L-mannaric acid.
Tetrahedron, 56, 3219-3225 (2000).
M. D. Hamalainen, P. O. Markgren, W. Schaal, A. Karlen, B. Classon, L. Vrang, B. Samuelsson, A. Hallberg, and U. H. Danielson:
Characterization of a set of HIV-1 protease inhibitors using binding kinetics data from a biosensor-based screen.
Journal of Biomolecular Screening, 5, 353-359 (2000).
U. Bremberg, S. Lutsenko, N. F. Kaiser, M. Larhed, A. Hallberg, and C. Mobert:
Rapid and stereoselective C-C, C-O, C-N and C-S couplings via microwave accelerated palladium-catalyzed allylic substitutions.
Synthesis-Stuttgart, , 1004-1008 (2000).
E. Danelian, A. Karlen, R. Karlsson, S. Winiwarter, A. Hansson, S. Lofas, H. Lennernas, and M. D. Hamalainen:
SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: Correlation with fraction absorbed in humans.
Journal of Medicinal Chemistry, 43, 2083-2086 (2000).
C. Coley, R. Woodward, A. M. Johansson, P. G. Strange, and L. H. Naylor:
Effect of multiple serine/alanine mutations in the transmembrane spanning region V of the D-2 dopamine receptor on ligand binding.
Journal of Neurochemistry, 74, 358-366 (2000).
S. De Villiers, N. Lindblom, G. Kalayanov, S. Gordon, A. Malmerfelt, A. M. Johansson, and T. H. Svensson:
Active immunization against nicotine can suppress the nicotine- induced stimulation of brain dopaminergic reward pathways.
Nordic Journal of Psychiatry, 54, 104-104 (2000).
P. Stenberg, U. Norinder, K. Luthman, and P. Artursson:
Computational methods for the prediction of intestinal drug permeability.
Abstracts of Papers of the American Chemical Society, 220, 31-COMP (2000).
J. T. Alder, A. M. Johansson, and P. G. Strange:
The relative binding affinities of a series of 2- (dipropylamino)tetralins at the human 5-HT1A receptor expressed in CHO cells.
British Journal of Pharmacology, 129, 242P (2000).
S. Sundquist, A. R. Modiri, B. M. Nilsson, U. Hacksell, P. G. Gillberg, and L. Nilvebrant:
Pharmacological characterisation of the enantiomers of BM-5, a muscarinic partial agonist with opposed enantioselectivity between affinity and efficacy.
Pharmacology & Toxicology, 86, 44-50 (2000).
T. Linnanen, M. Brisander, L. Unelius, G. Sundholm, U. Hacksell, and A. M. Johansson:
Derivatives of (R)-1,11-methyleneaporphine: Synthesis, structure, and interactions with G-protein coupled receptors.
Journal of Medicinal Chemistry, 43, 1339-1349 (2000).