K. S. A. Vallin, M. Larhed, and A. Hallberg:
Aqueous DMF-potassium carbonate as a substitute for thallium and silver additives in the palladium-catalyzed conversion of aryl bromides to acetyl arenes.
Journal of Organic Chemistry, 66, 4340-4343 (2001).
A. Johansson, I. Hubatsch, E. Akerblom, G. Lindeberg, S. Winiwarter, U. H. Danielson, and A. Hallberg:
Inhibition of hepatitis C virus NS3 protease activity by product-based peptides is dependent on helicase domain.
Bioorganic & Medicinal Chemistry Letters, 11, 203-206 (2001).
M. Alterman, H. Sjobom, P. Safsten, P. O. Markgren, U. H. Danielson, M. Hamalainen, S. Lofas, J. Hulten, B. Classon, B. Samuelsson, and A. Hallberg:
P1/P1 ' modified HIV protease inhibitors as tools in two new sensitive surface plasmon resonance biosensor screening assays.
European Journal of Pharmaceutical Sciences, 13, 203-212 (2001).
M. Graffner-Nordberg, K. Kolmodin, J. Aqvist, S. F. Queener, and A. Hallberg:
Design, synthesis, computational prediction, and biological evaluation of ester soft drugs as inhibitors of dihydrofolate reductase from Pneumocystis carinii.
Journal of Medicinal Chemistry, 44, 2391-2402 (2001).
W. Schaal, A. Karlsson, G. Ahlsen, J. Lindberg, H. O. Andersson, U. H. Danielson, B. Classon, T. Unge, B. Samuelsson, J. Hulten, A. Hallberg, and A. Karlen:
Synthesis and comparative molecular field analysis (CoMFA) of symmetric and nonsymmetric cyclic sulfamide HIV-1 protease inhibitors.
Journal of Medicinal Chemistry, 44, 155-169 (2001).
A. Muhlman, B. Classon, A. Hallberg, and B. Samuelsson:
Synthesis of potent C-2-symmetric, diol-based HIV-1 protease inhibitors. Investigation of thioalkyl and thioaryl P1/P1 ' substituents.
Journal of Medicinal Chemistry, 44, 3402-3406 (2001).
M. Larhed and A. Hallberg:
Microwave-assisted high-speed chemistry: a new technique in drug discovery.
Drug Discovery Today, 6, 406-416 (2001).
S. Lindman, G. Lindeberg, A. Gogoll, F. Nyberg, A. Karlen, and A. Hallberg:
Synthesis, receptor binding affinities and conformational properties of cyclic methylenedithioether analogues of angiotensin II.
Bioorganic & Medicinal Chemistry, 9, 763-772 (2001).
D. Pyring, J. Lindberg, A. Rosenquist, G. Zuccarello, I. Kvarnstrom, H. Zhang, L. Vrang, T. Unge, B. Classon, A. Hallberg, and B. Samuelsson:
Design and synthesis of potent C-2-symmetric diol-based HIV-1 protease inhibitors: Effects of fluoro substitution.
Journal of Medicinal Chemistry, 44, 3083-3091 (2001).
K. Olofsson, H. Sahlin, M. Larhed, and A. Hallberg:
Regioselective palladium-catalyzed synthesis of beta-arylated primary allylamine equivalents by an efficient Pd-N coordination.
Journal of Organic Chemistry, 66, 544-549 (2001).
P. Nilsson, M. Larhed, and A. Hallberg:
Highly regioselective, sequential, and multiple palladium- catalyzed arylations of vinyl ethers carrying a coordinating auxiliary: An example of a Heck triarylation process.
Journal of the American Chemical Society, 123, 8217-8225 (2001).
A. Muhlman, J. Lindberg, B. Classon, T. Unge, A. Hallberg, and B. Samuelsson:
Synthesis of novel, potent, diol-based HIV-1 protease inhibitors via intermolecular pinacol homocoupling of (2S)-2- benzyloxymethyl-4-phenylbutanal.
Journal of Medicinal Chemistry, 44, 3407-3416 (2001).
C. Lagerquist, F. Beigi, A. Karlen, H. Lennernas, and P. Lundahl:
Effects of cholesterol and model transmembrane proteins on drug partitioning into lipid bilayers as analysed by immobilized- liposome chromatography.
Journal of Pharmacy and Pharmacology, 53, 1477-1487 (2001).
L. Afzelius, I. Zamora, M. Ridderstrom, T. B. Andersson, A. Karlen, and C. M. Masimirembwa:
Competitive CYP2C9 inhibitors: Enzyme inhibition studies, protein homology modeling, and three-dimensional quantitative structure-activity relationship analysis.
Molecular Pharmacology, 59, 909-919 (2001).
P. Prusis, R. Muceniece, P. Andersson, C. Post, T. Lundstedt, and J. E. S. Wikberg:
PLS modeling of chimeric MS04/MSH-peptide and MC1/MC3-receptor interactions reveals a novel method for the analysis of ligand- receptor interactions.
Biochimica Et Biophysica Acta-Protein Structure and Molecular Enzymology, 1544, 350-357 (2001).
P. M. Andersson, A. Boman, E. Seifert, A. Skottner, and T. Lundstedt:
Ligands to the melanocortin receptors.
Expert Opinion On Therapeutic Patents, 11, 1583-1592 (2001).
P. M. Andersson, M. Sjostrom, S. Wold, and T. Lundstedt:
Strategies for subset selection of parts of an in-house chemical library.
Journal of Chemometrics, 15, 353-369 (2001).
P. Artursson, K. Palm, and K. Luthman:
Caco-2 monolayers in experimental and theoretical predictions of drug transport.
Advanced Drug Delivery Reviews, 46, 27-43 (2001).
T. Linnanen, M. Brisander, N. Mohell, and A. M. Johansson:
Serotonergic and dopaminergic activities of rigidified (R)- aporphine derivatives.
Bioorganic & Medicinal Chemistry Letters, 11, 367-370 (2001).
P. Martinez-Alvarado, A. Dagnino-Subiabre, I. Paris, D. Metodiewa, C. J. Welch, C. Olea-Azar, P. Caviedes, R. Caviedes, and J. Segura-Aguilar:
Possible role of salsolinol quinone methide in the decrease of RCSN-3 cell survival.
Biochemical and Biophysical Research Communications, 283, 1069-1076 (2001).
K. Janne, J. Pettersen, N. O. Lindberg, and T. Lundstedt:
Hierarchical principal component analysis (PCA) and projection to latent structure (PLS) technique on spectroscopic data as a data pretreatment for calibration.
Journal of Chemometrics, 15, 203-213 (2001).
T. Linnanen, M. Brisander, L. Unelius, S. Rosqvist, G. Nordvall, U. Hacksell, and A. M. Johansson:
Atropisomeric derivatives of 2 ',6 '-disubstituted (R)-11- phenylaporphine: Selective serotonin 5-HT7 receptor antagonists.
Journal of Medicinal Chemistry, 44, 1337-1340 (2001).