Papers

A. Dahlgren, I. Kvarnstrom, L. Vrang, E. Hamelink, A. Hallberg, A. Rosenquist, and B. Samuelsson:

Solid-phase library synthesis of reversed-statine type inhibitors of the malarial aspartyl proteases plasmepsin I and II.

Bioorganic & Medicinal Chemistry, 11, 827-841 (2003).

 

J. Georgsson, A. Hallberg, and M. Larhed:

Rapid palladium-catalyzed synthesis of esters from aryl halides utilizing Mo(CO)(6) as a solid carbon monoxide source.

Journal of Combinatorial Chemistry, 5, 350-352 (2003).

 

I. Gunnarsson, P. Andersson, J. Wikberg, and T. Lundstedt:

Multivariate analysis of G protein-coupled receptors.

Journal of Chemometrics17, 82-92 (2003).

 

A. Johansson, A. Poliakov, E. Akerblom, K. Wiklund, G. Lindeberg, S. Winiwarter, U. H. Danielson, B. Samuelsson, and A. Hallberg:

Acyl sulfonamides as potent protease inhibitors of the hepatitis C virus full-length NS3 (protease-helicase/NTPase): A comparative study of different C-terminals.

Bioorganic & Medicinal Chemistry, 11, 2551-2568 (2003).

 

S. Lindman, G. Lindeberg, P. A. Frandberg, F. Nyberg, A. Karlen, and A. Hallberg:

Effect of 3-5 monocyclizations of angiotensin II and 4- aminoPhe(6)-Ang II on AT(2) receptor affinity.

Bioorganic & Medicinal Chemistry, 11, 2947-2954 (2003).

 

P. Nilsson, M. Larhed, and A. Hallberg:

A new highly asymmetric chelation-controlled heck arylation.

Journal of the American Chemical Society, 125, 3430-3431 (2003).

 

D. Noteberg, E. Hamelink, J. Hulten, M. Wahlgren, L. Vrang, B. Samuelsson, and A. Hallberg:

Design and synthesis of plasmepsin I and plasmepsin II inhibitors with activity in Plasmodium falciparum-infected cultured human erythrocytes.

Journal of Medicinal Chemistry, 46, 734-746 (2003).

 

K. Oscarsson, A. Poliakov, S. Oscarson, U. H. Danielson, A. Hallberg, and B. Samuelsson:

Peptide-based inhibitors of hepatitis C virus full-length NS3 (protease-helicase/NTPase): Model compounds towards small molecule inhibitors.

Bioorganic & Medicinal Chemistry, 11, 2955-2963 (2003).

 

K. Oscarsson, S. Oscarson, L. Vrang, E. Hamelink, A. Hallberg, and B. Samuelsson:

New potent C-2-symmetric malaria plasmepsin I and II inhibitors.

Bioorganic & Medicinal Chemistry, 11, 1235-1246 (2003).

 

K. Oscarsson, M. Lahmann, J. Lindberg, J. Kangasmetsa, T. Unge, S. Oscarson, A. Hallberg, and B. Samuelsson:

Design and synthesis of HIV-1 protease inhibitors. Novel tetrahydrofuran P2/P2 '-groups interacting with Asp29/30 of the HIV-1 protease. Determination of binding from X-ray crystal structure of inhibitor protease complex.

Bioorganic & Medicinal Chemistry, 11, 1107-1115 (2003).

 

B. Schmidt, C. Kuhn, D. K. Ehlert, G. Lindeberg, S. Lindman, A. Karlen, and A. Hallberg:

A frame shifted disulfide bridged analogue of angiotensin II.

Bioorganic & Medicinal Chemistry, 11, 985-990 (2003).

 

Y. Q. Wan, X. Y. Wu, M. A. Kannan, and M. Alterman:

Boron trichloride as an efficient and selective agent for deprotection of tert-butyl aryl sulfonamides.

Tetrahedron Letters, 44, 4523-4525 (2003).

 

Y. Q. Wan, M. Alterman, M. Larhed, and A. Hallberg:

Formamide as a combined ammonia synthon and carbon monoxide source in fast palladium-catalyzed aminocarbonylations of aryl halides.

Journal of Combinatorial Chemistry, 5, 82-84 (2003).

 

S. Winiwarter, F. Ax, H. Lennernas, A. Hallberg, C. Pettersson, and A. Karlen:

Hydrogen bonding descriptors in the prediction of human in vivo intestinal permeability.

Journal of Molecular Graphics & Modelling, 21, 273-287 (2003).