A. K. Mahalingam; X. Y. Wu; M. Alterman:
Convenient removal of N-tert-butyl from amides with scandium triflate
Tetrahedron Lett., 47 (2006) 417.
A. K. Mahalingam; X. Y. Wu; M. Alterman; Y. Q. Wan; M. Alterman:
Scandium triflate as an efficient and recyclable catalyst for the deprotection of tert-butyl aryl sulfonamides
Synth. Commun., 35 (2006) 3051.
K. Ersmark, M. Nervall, H. Gutiérrez-de-Terán, E. Hamelink, L. K. Janka, J. C. Clemente, B. M. Dunn, A. Gogoll, B. Samuelsson, J. Åqvist, A. Hallberg:
Macrocyclic inhibitors of the malarial aspartic proteases plasmepsin I, II, and IV.
Bioorg Med Chem, 14 (2006) 2197-2208.
K. Ersmark, B. Samuelsson, A. Hallberg:
Plasmepsins as potential targets for new antimalarial therapy.
Medicinal Research Reviews, 26 (2006) 626-666.
P.O. Johansson, M. Bäck, I. Kvarnström, K. Jansson, L. Vrang, E. Hamelink, A. Hallberg, A. Rosenquist, B. Samuelsson:
Potent inhibitors of the hepatitis C virus NS3 protease: Use of a novel P2 cyclopentane-derived template.
Bioorg Med Chem, 14 (2006) 5136-5151.
H. Gutiérrez-de-Terán, M. Nervall, K. Ersmark, P. Lie, L.K. Janka, B. Dunn, A. Hallberg, J. Åqvist:
Inhibitor binding to the plasmepsin IV aspartic protease from Plasmodium falciparum.
Biochem,45 (2006) 10529-10541.
O. Lagerlund, M. Larhed:
Microwave-Promoted Aminocarbonylations of Aryl Chlorides Using Mo(CO)6 as a Solid Carbon Monoxide Source.
J. Comb. Chem., 8 (2006) 4-6.
P. Appukkuttan, E. Van der Eycken:
Microwave-Assisted Natural Product Chemistry.
Top. Curr. Chem., 266 (2006) 1-49.
M. Erdélyi, A. Karlén, A. Gogoll:
A New Tool in Peptide Engineering: A Photoswitchable Stilbene-type beta-Hairpin Mimetic.
Chemistry 12, 403-412 (2006)
P.-A. Enquist, J. Lindh, P. Nilsson and M. Larhed*:
Open-Air Oxidative Heck Reactions at Room Temperature.
Green Chemistry. 8 (2006) 338-343.
X. Wu, J. Wannberg and M. Larhed*:
Hydroxylamine as an Ammonia Equivalent in Microwave-Enhanced Aminocarbonylations.
Tetrahedron. 62 (2006) 4665-4670.
A. Axen, G. Lindeberg, H. Demaegdt, G. Vauquelin, A. Karlen, M. Hallberg:
Cyclic insulin-regulated aminopeptidase (IRAP)/AT(4) receptor ligands.
Journal of Peptide Science 12 (2006) 705-713.
J. Georgsson, U. Rosenström, C. Wallinder, H. Beaudry, B. Plouffe, G. Lindeberg, M. Botros, F. Nyberg, A. Karlén, N. Gallo-Payet, A. Hallberg:
Short pseudopeptides containing turn scaffolds with high AT2 receptor affinity.
Bioorg Med Chem, 14, (2006) 5963-5972.
H. Gold, A. Ax, L. Vrang, B. Samuelsson, A. Karlén, A. Hallberg and M. Larhed*:
Fast and Selective Synthesis of Novel Cyclic Sulfamide HIV-1 Protease Inhibitors under Controlled Microwave Heating.
Tetrahedron. 62 (2006) 4671-4675.
A. Arefalk, J. Wannberg, M. Larhed* and A. Hallberg:
Stereoselective Synthesis of 3-Aminoindan-1-ones and Subsequent Incorporation into HIV-1 Protease Inhibitors.
J. Org. Chem. 71 (2006) 1265-1268.
X. Wu, J. K. Ekegren and M. Larhed*:
Microwave-Promoted Aminocarbonylation of Aryl Iodides, Aryl Bromides and Aryl Chlorides in Water.
Organometallics. 25 (2006) 1434-1439.
J. K. Ekegren, N. Ginman, Å. Johansson, H. Wallberg, M. Larhed, B. Samuelsson, T. Unge, and A. Hallberg*:
Microwave Accelerated Synthesis of P1'-Extended HIV-1 Protease Inhibitors Encompassing a Tertiary Alcohol in the Transition-State Mimicking Scaffold.
J. Med. Chem. 49 (2006) 1828-1832.
G. K. Datta, H. von Schenck, A. Hallberg, M. Larhed*:
Selective Terminal Heck Arylation of Vinyl Ethers with Aryl Chlorides: A Combined Experimental-Computational Approach Including Synthesis of Betaxolol.
J. Org. Chem. 71 (2006) 3896-3903.
S. D. Peterson, W. Schaal and A. Karlén:
Improved CoMFA Modeling by Optimization of Settings.
Journal of Chemical Information and Modeling 46 (2006) 1334-1343.
M. Jacobsson, A. Karlén:
Ligand Bias of Scoring Functions in Structure-Based Virtual Screening.
Journal of Chemical Information and Modeling Web Release Date: January 4, 2006
J. Wannberg, Y. A. Sabnis, L. Vrang, B. Samuelsson, A. Karlén, A. Hallberg and M. Larhed*:
A New Structural Theme in C2-Symmetric HIV-1 Protease Inhibitors: ortho-Substituted P1/P1’ Side Chains.
Bioorg. Med. Chem. 14 (2006) 5303-5315.
P. Nilsson, K. Olofsson and M. Larhed:
Microwave-Assisted and Metal-Catalyzed Coupling Reactions.
Top. Curr. Chem. 266 (2006) 103-144.
J. Wannberg, K. Ersmark and M. Larhed:
Microwave-Accelerated Synthesis of Protease Inhibitors.
Top. Curr. Chem. 266 (2006) 167-198.
P.-A. Enquist, P. Nilsson, P. Sjöberg and M. Larhed:
ESI-MS Detection of Reaction Intermediates in the Air-Promoted and Ligand-Modulated Oxidative Heck Reaction.
J. Org. Chem.71 (2006) 8779-8786.
J. K. Ekegren, J. Gising, H. Wallberg, M, Larhed, B. Samuelsson, A. Hallberg:
Variations of the P2 Group in HIV-1 Protease Inhibitors Encompassing a Tertiary Alcohol in the Transition-State Mimicking Scaffold.
Org. Biomol. Chem. (2006) 3040-3043.
U. Rosenström, C. Sköld, G. Lindeberg, M. Botros, F. Nyberg, A. Karlen, A. Hallberg:
Design, synthesis, and incorporation of a beta-turn mimetic in angiotensin II forming novel pseudopeptides with affinity for AT(1) and AT(2) receptors.
Journal of Medicinal Chemistry 49 (2006) 6133-6137.
C. Sköld, A. Karlén:
Development of CoMFA models of affinity and selectivity to angiotensin II type-1 and type-2 receptors.
J. Mol. Graph. Model. 26 (2006)
C. Sköld, S. Winiwarter, J. Wernevik, F. Bergstr&oum;m, L. Engström, R. Allen, K. Box, J. Comer, J. Mole, A. Hallberg, H. Lennern¨as, T. Lundstedt, A. L. Ungell, A. Karlen:
Presentation of a structurally diverse and commercially available drug data set for correlation and benchmarking studies.
J. Med. Chem. 49 (2006) 6660-6671.
R. Rönn, Y. A. Sabnis, T. Gossas, E. Åkerblom, U. H. Danielsson, B. Samuelsson, A. Hallberg, A. Johansson*:
Exploration of Acyl Sulfonamides as Carboxylic Acid Replacements in Protease Inhibitors of the Hepatitis C Virus Full-Length NS3.
Bioorg. Med. Chem., 14 (2006) 544-559.
X. Y. Wu, Y. Q. Wan, A. K. Mahalingam, A. M. S. Murugaiah, B. Plouffe, M. Botros, A. Karlen, M. Hallberg, N. Gallo-Payet, M. Alterman:
Selective angiotensin II AT(2) receptor agonists: Arylbenzylimidazole structure-activity relationships.
J. Med. Chem. 49 (2006) 7160-7168.
K. Lundstedt-Enkel, J. Gabrielsson, H. Olsman, E. Seifert, J. Pettersen, P.M. Lek, A. Boman, T. Lundstedt
Different multivariate approaches to material discovery, PAT and environmental process monitoring..
Chemomet. Intell. Lab. Syst. 84 (2006) 201-207.
H.S. Sharma, T. Lundstedt, A. Boman, P. Lek, E. Seifert, L. Wiklund, S.F. Ali.
A potent serotonin-modulating compound AP-267 attenuates morphine withdrawal-induced blood-brain barrier dysfunction in rats.
Annals of the New York Academy of Sciences. 1074 (2006) 482-496.
J. Gabrielsson, M. Sjöström, N.-O. Lindberg, A.-C. Pihl, T. Lundstedt.
Robustness testing of a tablet formulation using multivariate design.
Drug development and Industrial Pharmacy. 32 (2006) 297-307.
J. Gabrielsson, M. Sjöström, N.-O. Lindberg, A.-C. Pihl, T. Lundstedt.
Multivariate methods in the development of a new tablet formulation: Excipient mixtures and principal properties.
Drug development and Industrial Pharmacy. 32 (2006) 7-20.