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Organic Pharmaceutical Chemistry - Läkemedelskemi - Organisk Farmaceutisk Kemi > Research > Papers > Wiki Pages > 2007  

2007

O. Lagerlund, L.R. Odell, S. L. Mowbray, M. T. Nilsson, W. W. Krajcewski, A. Nordqvist, A. Karlén, M. Larhed:
Microwave-enhanced α-arylation of a protected glycine in water. Evaluation of 3-phenylglycine derivatives as inhibitors of the tuberculosis enzyme, Glutamine synthetase.
Comb. Chem. High Throughput Screen.,10 (2007) 783-789.
 
J. Lindh, P.-A. Enquist, Å. Pilotti, P. Nilsson, M. Larhed:
Efficient Palladium(II) catalysis under air. Base-free oxidative Heck reactions at room temperature or with microwave heating.
J. Org. Chem., 72 (2007) 7957-7962.
 
R.K. Arvela, S. Pasquini, M. Larhed:
Highly regioselective internal Heck arylation of hydroxyalkyl vinyl ethers by aryl halides in neat water.
J. Org. Chem., 72 (2007) 6390-6396.
 
A. Svennebring, P. Nilsson, M. Larhed:
Microwave-accelerated spiro-cyclizations of o-halobenzyl cyclohexenyl ethers by Palladium(0) catalysis.
J. Org. Chem., 72 (2007) 5851-5854.
 
J. Georgsson, C. Sköld, M. Botros, F. Nyberg, A. Karlén, A. Hallberg, M. Larhed:
Synthesis of a new class of drug-like angiotensin II C-terminal mimics with affinity for the AT2 receptor.
J. Med. Chem., 50 (2007) 1711-1715.
 
S. Röttger, P. J. R. Sjöberg, M. Larhed:
Microwave-enhanced copper-catalyzed N-arylation of free and protected amino acids in water.
J. Comb. Chem., 9 (2007) 204-209.
 
F. Thorstensson, F. Wångsell, I. Kvarnström, L. Vrang, E. Hamelink, K. Jansson, A. Hallberg, S. Rosenquist, B. Samuelsson:
Synthesis of novel potent hepatitis C virus NS3 protease inhibitors: discovery of 4-hydroxy-cyclopent-2-ene-1,2-dicarboxylic acid as a N-acyl-L-hydroxyproline bioisostere.
Bioorg Med Chem, 15 (2007) 827-838.
 
M. Larhed, J. Wannberg, A. Hallberg:
Controlled microwave heating as an enabling technology: Expedient synthesis of protease inhibitors in perspective.
QSAR Comb. Sci. (2007) 51-68.
 
P. Örtqvist, S. D. Peterson, E. Åkerblom, T. Gossas, Y. A. Sabnis, R. Fransson, G. Lindeberg, H. Danielson, A. Karlen, A. Sandström:
Phenylglycine as a novel P2 scaffold in hepatitis C virus NS3 protease inhibitors.
Bioorg. Med. Chem. 15 (2007) 1448-1474.
 
A. Poliakov, A. Sandström, E. Åkerblom, U. H. Danielson.
Mechanistic studies of electrophilic protease inhibitors of full length hepatic C virus (HCV) NS3.
J. Enzyme Inhib. Med. Chem. 22 (2007) 191-199.
 
G. Dahl, A. Sandström, E. Åkerblom, U. H. Danielson.
Resistance profiling of HCV protease inhibitors using full-length NS3.
Antivir. Ther. 12 (2007) 733-740.
 
R. Rönn, T. Gossas, Y. A. Sabnis, H. Daoud, E. Åkerblom, U. H. Danielson, A. Sandström.
Evaluation of a diverse set of potential P1 carboxylic acid bioisosteres in hepatitis C virus NS3 protease inhibitors.
Bioorg. Med. Chem. 15 (2007) 4057-4068.
 
G. Dahl, A. Sandström, E. Åkerblom, U. H. Danielson.
Effects on protease inhibition by modifying of helicase residues in hepatitis C virus nonstructural protein 3.
FEBS J. 274 (2007) 5979-5986.

Last modified at 2008-09-19 09:19  by Sorin Srbu