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- Research articles
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- G. K. Datta, M. Larhed*: High Stereoselectivity in Chelation-Controlled Intermolecular Heck Reactions with Aryl Chlorides, Vinyl Chlorides and Vinyl Triflates. Org. Biomol. Chem. 6 (2008) 674-676.
- A. Svennebring, Per J. R. Sjöberg, M. Larhed, P. Nilsson*: A mechanistic study on modern palladium catalyst precursors as new gateways to Pd(0) in cationic Heck reactions. Tetrahedron. 64 (2008) 1808-1812.
- X. Wu, P. Öhrngren, J. K. Ekegren, J. Unge, T. Unge, H. Wallberg, B. Samuelsson, A. Hallberg, M. Larhed*: Two-Carbon-Elongated HIV-1 Protease Inhibitors with a Tertiary-Alcohol-Containing Transition-State Mimic. J. Med. Chem. 51 (2008) 1053-1057.
- G. K. Datta, P. Nordeman, J. Dackenberg, P. Nilsson, A. Hallberg, Mats Larhed*: Enantiopure 2-Aryl-2-Methyl Cyclopentanones by a Chelation-Controlled Heck Reaction using Aryl Bromides: Expanded Preparative Scope and Effect of Ring Size on Reactivity and Selectivity. Tetrahedron: Asymmetry 19 (2008), 1120-1126.
- A. Nordqvist, M. Nilsson, S. Röttger, L. Odell, C. E.-L. Andersson, W. W. Krajewski, M. Larhed, S. L. Mowbray, A. Karlén*: Hit identification of Mycobacterium tuberculosis glutamine synthetase. –Aiming for the amino acid binding site Bioorg. Med. Chem. 16 (2008), 5501-5513.
- P. Appukkuttan, L. Axelsson, E. Van der Eycken, Mats Larhed*: Microwave-Enhanced, Mo(CO)6-Mediated, Palladium-Catalyzed Aminocarbonylation of Aryl Halides Using Allylamine: From Exploration to Scale-Up. Tetrahedron Lett. 49 (2008) 5625-5628.
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S. Pasquini, C. Mugnaini, C. Tintori, M. Botta, A. Trejos, R. K. Arvela, M. Larhed, M. Witvrouw, Z. Debyser, F. Corelli*: Investigations on the 4-Quinolone-3- carboxylic Acid Motif. 1. Synthesis and Structure-Activity Relationship of a Class of Human Immunodeficiency Virus Type 1 Integrase Inhibitors. J. Med. Chem. 51 (2008) 5125-5129.
- A. Trejos, J. Sävmarker, S. Schlummer, G. K. Datta, P. Nilsson, M. Larhed: Stereoselective Heck arylation of a functionalized cyclopentyl ether using (S)-N-methyl-pyrrolidine as the stereochemical controller. Tetrahedron, 64 (2008) 8746-8751.
- L. R. Odell, J. Sävmarker, M. Larhed*: Microwave-promoted aminocarbonylation of aryl triflates using Mo(CO)6 as a solid CO source. Tetrahedron Lett. 49 (2008) 6115-6118.
- K. M. Orrling, X. Wu, F. Russo, M. Larhed*: Fast, Acid-Free, and Selective Lactamization of Lactones in Ionic Liquids. J. Org. Chem. 73 (2008) 8627-8630.
F. Thorstensson, F. Wångsell, I. Kvarnström, L. Vrang, E. Hamelink, K. Jansson, A. Hallberg, S. Rosenquist, B. Samuelsson:
Synthesis of novel potent hepatitis C virus NS3 protease inhibitors: discovery of 4-hydroxy-cyclopent-2-ene-1,2-dicarboxylic acid as a N-acyl-L-hydroxyproline bioisostere.
Bioorg Med Chem, 15 (2007) 827-838.
P. Örtqvist, S. D. Peterson, E. Åkerblom, T. Gossas, Y. A. Sabnis, R. Fransson, G. Lindeberg, H. Danielson, A. Karlen, A. Sandström:
Phenylglycine as a novel P2 scaffold in hepatitis C virus NS3 protease inhibitors.
Bioorg. Med. Chem. 15 (2007) 1448-1474.
R. Rönn, A. Lampa, S. D. Peterson , T. Gossas, E. Åkerblom, U. H. Danielson, A. Karlén, A. Sandström.
Hepatitis C virus NS3 protease inhibitors comprising a novel aromatic P1 moiety.
Bioorg. Med. Chem. 16 (2008) 2955-2969.
R. Fransson, M. Botros, F. Nyberg, G. Lindeberg, A. Sandström, M. Hallberg.
Small peptides mimicking substance P (1-7) and encompassing a C-terminal amide functionality.
Neuropeptides. 42 (2008) 31-37.
J. Nurbo, S. D. Peterson, G. Dahl, U. H. Danielson, A. Karlén, A. Sandstöm.
b-Amino acid substitutions and structure-based CoMFA modeling of hepatitis C virus NS3 protease inhibitors.
Bioorg. Med. Chem. 16 (2008) 5590-5605.
R. Rönn, A. Sandström.
New Developments in the Discovery of Agents to Treat Hepatitis C.
Curr. Top. Med. Chem. (2008) 533-562.
Book chapters
P. Nilsson, K. Olofsson and M. Larhed: Focus on Regioselectivity and Product Outcome in Organic Synthesis. In The Heck Reaction, M. Oestreich, Ed. John Wiley and Sons, 2008, 133-162.
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Last modified at 2009-08-07 09:28 by Mats Larhed
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