U. Nillroth, L. Vrang, P. O. Markgren, J. Hulten, A. Hallberg, and U. H. Danielson:
Human immunodeficiency virus type 1 proteinase resistance to symmetric cyclic urea inhibitor analogs
Antimicrobial Agents and Chemotherapy, 41, 2383-2388 (1997)
B. Schmidt, S. Lindman, W. M. Tong, G. Lindeberg, A. Gogoll, Z. N. Lai, M. Thornwall, B. Synnergren, A. Nilsson, C. J. Welch, M. Sohtell, C. Westerlund, F. Nyberg, A. Karlen, and A. Hallberg:
Design, synthesis, and biological activities of four angiotensin II receptor ligands with gamma-turn mimetics replacing amino acid residues 3-5
Journal of Medicinal Chemistry, 40, 903-919 (1997)
L. Ripa and A. Hallberg:
Intramolecular enantioselective palladium-catalyzed Heck arylation of cyclic enamides
Journal of Organic Chemistry, 62, 595-602 (1997)
C. Kuhn, G. Lindeberg, A. Gogoll, A. Hallberg, and B. Schmidt:
Fmoc protected peptide mimetic based on a cyclohexane framework and incorporation into angiotensin II
Tetrahedron, 53, 12497-12504 (1997)
J. Branalt, I. Kvarnstrom, B. Classon, B. Samuelsson, U. Nillroth, U. H. Danielson, A. Karlen, and A. Hallberg:
A convenient synthesis of 1-(S)-[1'-(S)-(t- butyloxycarbonylamino)-2'-phenylethyl]oxirane. A useful building block in the synthesis of HIV protease inhibitors
Tetrahedron Letters, 38, 3483-3486 (1997)
D. Noteberg, J. Branalt, I. Kvarnstrom, B. Classon, B. Samuelsson, U. Nillroth, H. Danielson, A. Karlen, and A. Hallberg:
Synthesis of enantiomerically pure cis and trans 2- aminocyclopentanecarboxylic acids. Use of proline replacements in potential HIV-protease inhibitors
Tetrahedron, 53, 7975-7984 (1997)
M. Larhed, M. Hoshino, S. Hadida, D. P. Curran, and A. Hallberg:
Rapid fluorous Stille coupling reactions conducted under microwave irradiation
Journal of Organic Chemistry, 62, 5583-5587 (1997)
M. Larhed and A. Hallberg:
Direct synthesis of cyclic ketals of acetophenones by palladium-catalyzed arylation of hydroxyalkyl vinyl ethers
Journal of Organic Chemistry, 62, 7858-7862 (1997)
L. Ripa, A. Hallberg, and J. Sandstrom:
Determination of absolute configurations of N-Formyl-3,3',4,4'- tetrahydrospiro[naphthalene-1(2H),2'(1'H)-pyridine] (2) and N- Formyl-3',4'-dihydrospiro[indan-1,2'(1'H)-pyridine] (3) by analysis of circular dichroism spectra. A case of two compounds with similar configuration but nearly mirror image CD spectra
Journal of the American Chemical Society, 119, 5701-5705 (1997)
K. Backbro, S. Lowgren, K. Osterlund, J. Atepo, T. Unge, J. Hulten, N. M. Bonham, W. Schaal, A. Karlen, and A. Hallberg:
Unexpected binding mode of a cyclic sulfamide HIV-1 protease inhibitor
Journal of Medicinal Chemistry, 40, 898-902 (1997)
A. Hallberg, W. Wobrock, A. I. Flossmann, K. N. Bower, K. J. Noone, A. Wiedensohler, H. C. Hansson, M. Wendisch, A. Berner, C. Kruisz, P. Laj, M. C. Facchini, S. Fuzzi, and B. G. Arends:
Microphysics of clouds: Model vs measurements
Atmospheric Environment, 31, 2453-2462 (1997)
J. Hulten, N. M. Bonham, U. Nillroth, T. Hansson, G. Zuccarello, A. Bouzide, J. Aqvist, B. Classon, U. H. Danielson, A. Karlen, I. Kvarnstrom, B. Samuelsson, and A. Hallberg:
Cyclic HIV-1 protease inhibitors derived from mannitol: Synthesis, inhibitory potencies, and computational predictions of binding affinities
Journal of Medicinal Chemistry, 40, 885-897 (1997)
H. Yu, Y. Liu, H. B. Li, A. R. Martin, U. Hacksell, and T. Lewander:
Pharmacodynamic and pharmacokinetic studies in rats of S-8-(2- furyl)- and R-8-phenyl-2-(di-n-propylamino)tetralin, two novel 5-HT1A receptor agonists in-vitro with different properties in- vivo
Journal of Pharmacy and Pharmacology, 49, 169-177 (1997)
J. M. Jansen, K. F. Koehler, M. H. Hedberg, A. M. Johansson, U. Hacksell, G. Nordvall, and J. P. Snyder:
Molecular design using the minireceptor concept
Journal of Chemical Information and Computer Sciences, 37, 812-818 (1997)
G. Johansson, S. Sundquist, G. Nordvall, B. M. Nilsson, M. Brisander, L. Nilvebrant, and U. Hacksell:
Antimuscarinic 3-(2-furanyl)quinuclidin-2-ene derivatives: Synthesis and structure-activity relationships
Journal of Medicinal Chemistry, 40, 3804-3819 (1997)
J. Segura Aguilar, S. Baez, M. Widersten, C. J. Welch, and B. Mannervik:
Human class mu glutathione transferases, in particular isoenzyme M2-2, catalyze detoxication of the dopamine metabolite aminochrome
Journal of Biological Chemistry, 272, 5727-5731 (1997)
C. J. Welch:
An experiment to demonstrate magnetic nonequivalence in proton NMR
Journal of Chemical Education, 74, 247-248 (1997)
K. Palm, P. Stenberg, K. Luthman, and P. Artursson:
Polar molecular surface properties predict the intestinal absorption of drugs in humans
Pharmaceutical Research, 14, 568-571 (1997)
M. Vasange, B. L. Liu, C. J. Welch, W. C. Rolfsen, and L. Bohlin:
The flavonoid constituents of two polypodium species (Calaguala) and their effect on the elastase release in human neutrophils
Planta Medica, 63, 511-517 (1997)
L. Grehn, U. Ragnarsson, and C. J. Welch:
Carbon-carbon and carbon-nitrogen spin-spin coupling in NMR spectroscopy - Simple examples based on isotope-labeled glycines
Journal of Chemical Education, 74, 1477-1479 (1997) 1996
M. Larhed and A. Hallberg:
Microwave-promoted palladium-catalyzed coupling reactions
Journal of Organic Chemistry, 16, 9582-9584 (1996)
L. Ripa and A. Hallberg:
Controlled double-bond migration in palladium-catalyzed intramolecular arylation of enamidines
Journal of Organic Chemistry, 61, 7147-7155 (1996)
G. Niklasson, I. Kvarnstrom, B. Classon, B. Samuelsson, U. Nillroth, H. Danielson, A. Karlen, and A. Hallberg:
Synthesis of C-2 symmetric potential inhibitors of HIV-1 protease from D-mannitol
Journal of Carbohydrate Chemistry, 15, 555-569 (1996)
C. Sonesson, M. Larhed, C. Nyqvist, and A. Hallberg:
Regiochemical control and suppression of double bond isomerization in the Heck arylation of 1-(methoxycarbonyl)-2,5- dihydropyrrole
Journal of Organic Chemistry, 61, 4756-4763 (1996)
M. Larhed, G. Lindeberg, and A. Hallberg:
Rapid microwave-assisted Suzuki coupling on solid-phase
Tetrahedron Letters, 37, 8219-8222 (1996)
M. AbdelRehim, A. Karlen, L. Zhang, M. Kamel, and M. Hassan:
Enantiomer separation of underivatized tocainide and related compounds by CGC using ammonia as carrier gas
Journal of Microcolumn Separations, 8, 151-156 (1996)
N. Garg, A. Gogoll, C. Westerlund, S. Sundell, A. Karlen, and A. Hallberg:
Preparation of cis-5-methoxy-and-7-methoxy-1-acetoxy- 1,2,3,4,4a,10a-hexahydro-9(10H)-phenanthrenone. An epoxide- arene reaction involving a selective 1,2-alkyl shift rearrangement
Tetrahedron, 52, 15209-15224 (1996)
G. EstenneBouhtou, K. Kullander, M. Karlsson, T. Ebendal, U. Hacksell, and K. Luthman:
Design, synthesis, tandem mass spectrometric sequencing and biological activity of NGF mimetics
International Journal of Peptide and Protein Research, 48, 337-346 (1996)
B. B. Hook, L. Cortizo, A. M. Johansson, A. WestlindDanielsson, N. Mohell, and U. Hacksell:
Derivatives of (R)- and (S)-5-fluoro-8-hydroxy-2- (dipropylamino)tetralin: Synthesis and interactions with 5-HT1A receptors
Journal of Medicinal Chemistry, 39, 4036-4043 (1996)
S. E. Hillver, L. Bjork, B. B. Hook, L. Cortizo, G. Nordvall, A. M. Johansson, A. Ertan, I. Csoregh, L. Johansson, T. Lewander, and U. Hacksell:
Synthesis and pharmacology of the enantiomers of UH301: Opposing interactions with 5-HT1A receptors
Chirality, 8, 531-544 (1996)
U. Appelberg, N. Mohell, and U. Hacksell:
Derivatives of 2-arylcyclopropylamine: Synthesis and interactions with 5-HT1A receptors
Bioorganic & Medicinal Chemistry Letters, 6, 415-420 (1996)
K. Palm, K. Luthman, A. L. Ungell, G. Strandlund, and P. Artursson:
Correlation of drug absorption with molecular surface properties
Journal of Pharmaceutical Sciences, 85, 32-39 (1996)
L. Arborelius, G. G. Nomikos, P. Hertel, P. Salmi, P. Grillner, B. B. Hook, U. Hacksell, and T. H. Svensson:
The 5-HT1A receptor antagonist (S)-UH-301 augments the increase in extracellular concentrations of 5-HT in the frontal cortex produced by both acute and chronic treatment with citalopram
Naunyn-Schmiedebergs Archives of Pharmacology, 353, 630-640 (1996)
P. Artursson, K. Palm, and K. Luthman:
Caco-2 monolayers in experimental and theoretical predictions of drug transport
Advanced Drug Delivery Reviews, 22, 67-84 (1996)
C. Liljebris, B. M. Nilsson, B. Resul, and U. Hacksell:
Regio- and stereoselective reactions of 17-phenyl-18,19,20- trinorprostaglandin F-2 alpha isopropyl ester
Journal of Organic Chemistry, 61, 4028-4034 (1996)
H. Yu, Y. Liu, U. Hacksell, and T. Lewander:
Oral cavity absorption of (R)-8-hydroxy-2-(di-n- propylamino)tetralin and (S)-8-acetyl-2-(di-n- propylamino)tetralin in the rat
Journal of Pharmacy and Pharmacology, 48, 41-45 (1996)
G. Nordvall, S. Sundquist, G. Johansson, G. Glas, L. Nilvebrant, and U. Hacksell:
3-(2-benzofuranyl)quinuclidin-2-ene derivatives: Novel muscarinic antagonists
Journal of Medicinal Chemistry, 39, 3269-3277 (1996)
G. G. Nomikos, L. Arborelius, B. B. Hook, U. Hacksell, and T. H. Svensson:
The 5-HT1A receptor antagonist (S)-UH-301 decreases dopamine release in the rat nucleus accumbens and striatum
Journal of Neural Transmission, 103, 541-554 (1996)
J. Vallgarda, U. Appelberg, L. E. Arvidsson, S. Hjorth, B. E. Svensson, and U. Hacksell:
trans-2-Aryl-N,N-dipropylcyclopropylamines: Synthesis and interactions with 5-HT1A receptors
Journal of Medicinal Chemistry, 39, 1485-1493 (1996)
A. Malmberg, B. B. Hook, A. M. Johansson, and U. Hacksell:
Novel (R)-2-amino-5-fluorotetralins: Dopaminergic antagonists and inverse agonists
Journal of Medicinal Chemistry, 39, 4421-4429 (1996)
H. Yu, Y. Liu, A. Malmberg, N. Mohell, U. Hacksell, and T. Lewander:
Differential serotoninergic and dopaminergic activities of the (R)- and the (S)-enantiomers of 2-(di-n-propylamino) tetralin
European Journal of Pharmacology, 303, 151-162 (1996)