Organic Pharmaceutical Chemistry

Our research interests encompass a range of targets of pharmaceutical interest including proteases and membrane bound G-protein coupled receptors (GPCRs). One of our primary themes is to identify novel and selective low molecular weight ligands for these targets. New strategies are developed for both the design and for the synthesis of small, drug-like molecules. Lead compounds are optimized using computer-aided techniques and are preferentially synthesized using high-speed chemistry.

Major indications that are addressed are infections caused by HIV and HCV (Hepatitis C Virus) as well as the infectious diseases Malaria and Tuberculosis. In addition, basic research on novel drug-like ligands with importance within the Renin/Angiotensin system are studied.

The Division provides several courses in the master's programs in Pharmacy and Dispensing Pharmacy. The Division is responsible for undergraduate teaching in organic pharmaceutical chemistry and medicinal chemistry at the Faculty of Pharmacy.